Effective Unsupervised Author Disambiguation with Relative Frequencies

This work addresses the problem of author name homonymy in the Web of Science. Aiming for an efficient, simple and straightforward solution, we introduce a novel probabilistic similarity measure for author name disambiguation based on feature overlap. Using the researcher-ID available for a subset of the Web of Science, we evaluate the application of this measure in the context of agglomeratively clustering author mentions. We focus on a concise evaluation that shows clearly for which problem setups and at which time during the clustering process our approach works best. In contrast to most other works in this field, we are sceptical towards the performance of author name disambiguation methods in general and compare our approach to the trivial single-cluster baseline. Our results are presented separately for each correct clustering size as we can explain that, when treating all cases together, the trivial baseline and more sophisticated approaches are hardly distinguishable in terms of evaluation results. Our model shows state-of-the-art performance for all correct clustering sizes without any discriminative training and with tuning only one convergence parameter.Comment: Proceedings of JCDL 201

Does updating education curricula accelerate technology adoption in the workplace? Evidence from dual vocational education and training curricula in Switzerland

In an environment of accelerating technological change and increasing digitalization, firms need to adopt new technologies faster than ever before to stay competitive. This paper examines whether updates of education curricula help to bring new technologies faster into firms’ workplaces. We study technology changes and curriculum updates from an early wave of digitalization (i.e., computer-numerically controlled machinery, computer-aided design, and desktop publishing software). We take a text-as-data approach and tap into two novel data sources to measure change in educational content and the use of technology at the workplace: first, vocational education curricula and, second, firms’ job advertisements. To examine the causal effects of adding new technology skills to curricula on the diffusion of these technologies in firms’ workplaces (measured by job advertisements), we use an event study design. Our results show that curriculum updates substantially shorten the time it takes for new technologies to arrive in firms’ workplaces, especially for mainstream firms

The role of fields of study for the effects of higher education institutions on regional firm location

The literature on knowledge spillovers provides evidence that higher education institutions (HEIs) positively affect regional firm location (i.e., start-ups or firms located in a region). However, less is known about how HEIs in different fields of study impact regional firm location in different industries. To investigate this question, we exploit the establishment of universities of applied sciences (UASs)—bachelor’s degree-granting three-year HEIs in Switzerland. We find that the effects of UASs are heterogeneous across fields of study and industries. UASs specializing in “chemistry and the life sciences” and “business, management, and services” are the only UASs that positively affect regional firm location across several industries. Positive effects emerge in service industries characterized by radical service, incremental product, or process innovations. Thus, UASs are not a one-size-fits-all solution for increasing regional firm location. Instead, only UASs specializing in particular fields of study positively influence firm location in certain industries

Different degrees of skill obsolescence across hard and soft skills and the role of lifelong learning for labor market outcomes

This paper examines the role of lifelong learning in counteracting skill depreciation and obsolescence. We differentiate between occupations with more hard skills versus more soft skills and draw on representative job advertisement data that contain machine-learning categorized skill requirements and cover the Swiss job market in great detail across occupations (from 1950 to 2019). We examine lifelong learning effects for “harder” versus “softer” occupations, thereby analyzing the role of training in counteracting skill depreciation in occupations that are differently affected by skill depreciation. Our results reveal novel empirical patterns regarding the benefits of lifelong learning, which are consistent with theoretical explanations based on structurally different skill depreciation rates: In harder occupations, with large shares of fast-depreciating hard skills, the role of lifelong learning is primarily as a hedge against unemployment risks rather than a boost to wages. By contrast, in softer occupations, in which workers build on more value-stable soft-skill foundations, the role of lifelong learning instead lies mostly in acting as a boost for upward career mobility and leads to larger wage gains

Towards hierarchical affiliation resolution: framework, baselines, dataset

Author affiliations provide key information when attributing academic performance like publication counts. So far, such measures have been aggregated either manually or only to top-level institutions, such as universities. Supervised affiliation resolution requires a large number of annotated alignments between affiliation strings and known institutions, which are not readily available. We introduce the task of unsupervised hierarchical affiliation resolution, which assigns affiliations to institutions on all hierarchy levels (e.g. departments), discovering the institutions as well as their hierarchical ordering on the fly. From the corresponding requirements, we derive a simple conceptual framework based on the subset partial order that can be extended to account for the discrepancies evident in realistic affiliations from the Web of Science. We implement initial baselines and provide datasets and evaluation metrics for experimentation. Results show that mapping affiliations to known institutions and discovering lower-level institutions works well with simple baselines, whereas unsupervised top-level- and hierarchical resolution is more challenging. Our work provides structured guidance for further in-depth studies and improved methodology by identifying and discussing a number of observed difficulties and important challenges that future work needs to address

Tertiary education expansion and regional firm development

This study investigates the impact of a tertiary education expansion on regional firm development, as measured by average profits per firm. We exploit the quasi-random establishment of universities of applied sciences (UASs) – bachelor’s degree-granting three-year colleges teaching and conducting applied research – to construct treatment and control groups and to apply both a difference-in-differences model and an event study design. We find that after the establishment of new UASs in Switzerland, average profits per firm in the treated municipalities increase by 19.6% more than in the control group. This increase corresponds roughly to an additional annual growth in average profits per firm in the treatment group of 0.7%. The effects start shortly after the establishment of UASs but also persist over a period of up to 10 years

DynaVenn: web-based computation of the most significant overlap between ordered sets

Background: In many research disciplines, ordered lists are compared. One example is to compare a subset of all significant genes or proteins in a primary study to those in a replication study. Often, the top of the lists are compared using Venn diagrams, ore more precisely Euler diagrams (set diagrams showing logical relations between a finite collection of different sets). If different cohort sizes, different techniques or algorithms for evaluation were applied, a direct comparison of significant genes with a fixed threshold can however be misleading and approaches comparing lists would be more appropriate. Results: We developed DynaVenn, a web-based tool that incrementally creates all possible subsets from two or three ordered lists and computes for each combination a p-value for the overlap. Respectively, dynamic Venn diagrams are generated as graphical representations. Additionally an animation is generated showing how the most significant overlap is reached by backtracking. We demonstrate the improved performance of DynaVenn over an arbitrary cut-off approach on an Alzheimer’s Disease biomarker set. Conclusion: DynaVenn combines the calculation of the most significant overlap of different cohorts with an intuitive visualization of the results. It is freely available as a web service at http://www.ccb.uni-saarland.de/dynavenn

PLSDB: a resource of complete bacterial plasmids

The study of bacterial isolates or communities requires the analysis of the therein included plasmids in order to provide an extensive characterization of the organisms. Plasmids harboring resistance and virulence factors are of especial interest as they contribute to the dissemination of antibiotic resistance. As the number of newly sequenced bacterial genomes is growing a comprehensive resource is required which will allow to browse and filter the available plasmids, and to perform sequence analyses. Here, we present PLSDB, a resource containing 13 789 plasmid records collected from the NCBI nucleotide database. The web server provides an interactive view of all obtained plasmids with additional meta information such as sequence characteristics, sample-related information and taxonomy. Moreover, nucleotide sequence data can be uploaded to search for short nucleotide sequences (e.g. specific genes) in the plasmids, to compare a given plasmid to the records in the collection or to determine whether a sample contains one or multiple of the known plasmids (containment analysis). The resource is freely accessible under https://ccbmicrobe.cs.uni-saarland.de/plsdb/

Education expansion and high-skill job opportunities for workers: Does a rising tide lift all boats?

We examine how education expansions affect the job opportunities for workers with and without the new education. To identify causal effects, we exploit a quasi-random establishment of Universities of Applied Sciences (UASs), bachelor-granting three-year colleges that teach and conduct applied research. By applying machine-learning methods to job advertisement data, we analyze job content before and after the education expansion. We find that, in regions with the newly established UASs, not only job descriptions of the new UAS graduates but also job descriptions of workers without this degree (i.e., middle-skilled workers with vocational training) contain more high-skill job content. This upskilling in job content is driven by an increase in high-skill R&D-related tasks and linked to employment and wage gains. The task spillovers likely occur because UAS graduates with applied research skills build a bridge between middle-skilled workers and traditional university graduates, facilitating the integration of the former into R&D-related tasks

Critical Protein–Protein Interactions Determine the Biological Activity of Elk-1, a Master Regulator of Stimulus-Induced Gene Transcription

Elk-1 is a transcription factor that binds together with a dimer of the serum response factor (SRF) to the serum-response element (SRE), a genetic element that connects cellular stimulation with gene transcription. Elk-1 plays an important role in the regulation of cellular proliferation and apoptosis, thymocyte development, glucose homeostasis and brain function. The biological function of Elk-1 relies essentially on the interaction with other proteins. Elk-1 binds to SRF and generates a functional ternary complex that is required to activate SRE-mediated gene transcription. Elk-1 is kept in an inactive state under basal conditions via binding of a SUMO-histone deacetylase complex. Phosphorylation by extracellular signal-regulated protein kinase, c-Jun N-terminal protein kinase or p38 upregulates the transcriptional activity of Elk-1, mediated by binding to the mediator of RNA polymerase II transcription (Mediator) and the transcriptional coactivator p300. Strong and extended phosphorylation of Elk-1 attenuates Mediator and p300 recruitment and allows the binding of the mSin3A-histone deacetylase corepressor complex. The subsequent dephosphorylation of Elk-1, catalyzed by the protein phosphatase calcineurin, facilitates the re-SUMOylation of Elk1, transforming Elk-1 back to a transcriptionally inactive state. Thus, numerous protein–protein interactions control the activation cycle of Elk-1 and are essential for its biological function